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Leonie Wyffels Selected Research

duramycin

1/2018[99mTc]duramycin for cell death imaging: Impact of kit formulation, purification and species difference.
4/201799mTc-Duramycin SPECT Imaging of Early Tumor Response to Targeted Therapy: A Comparison with 18F-FDG PET.
1/2017Phosphatidylethanolamine targeting for cell death imaging in early treatment response evaluation and disease diagnosis.
12/2015Characterization of [(99m)Tc]Duramycin as a SPECT Imaging Agent for Early Assessment of Tumor Apoptosis.

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Leonie Wyffels Research Topics

Disease

15Neoplasms (Cancer)
03/2020 - 07/2014
8Alzheimer Disease (Alzheimer's Disease)
01/2019 - 01/2015
7Colorectal Neoplasms (Colorectal Cancer)
03/2020 - 12/2015
5Huntington Disease (Huntington's Disease)
01/2022 - 11/2018
5Nervous System Diseases (Neurological Disorders)
01/2021 - 05/2010
4Disease Progression
01/2022 - 01/2019
4Neuroinflammatory Diseases
01/2021 - 02/2016
4Inflammation (Inflammations)
01/2019 - 10/2012
3Hypoxia (Hypoxemia)
08/2019 - 01/2016
3Neoplasm Metastasis (Metastasis)
01/2017 - 07/2014
3Amyloidosis
01/2017 - 01/2015
2Status Epilepticus (Complex Partial Status Epilepticus)
01/2021 - 03/2017
2Obsessive-Compulsive Disorder (Disorder, Obsessive-Compulsive)
10/2020 - 11/2016
2Dementia (Dementias)
01/2019 - 01/2017
2Cognitive Dysfunction
01/2019 - 01/2017
2Epilepsy (Aura)
03/2017 - 11/2013
2Schizophrenia (Dementia Praecox)
02/2016 - 11/2013
2Reperfusion Injury
06/2012 - 06/2011
1Chronic Disease (Chronic Diseases)
01/2021
1Atherosclerosis
05/2020
1Atherosclerotic Plaque (Atheroma)
05/2020
1Neurodegenerative Diseases (Neurodegenerative Disease)
04/2020
1Brain Diseases (Brain Disorder)
01/2020
1Lung Neoplasms (Lung Cancer)
01/2019
1Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
01/2019
1Psychotic Disorders (Schizoaffective Disorder)
01/2019
1Traumatic Brain Injuries (Traumatic Brain Injury)
01/2019
1Necrosis
01/2017
1Amyloid Plaque
01/2016
1Breast Neoplasms (Breast Cancer)
07/2014
1Parkinson Disease (Parkinson's Disease)
11/2013
1Myocardial Ischemia (Ischemic Heart Diseases)
06/2012
1Drug Resistant Epilepsy
03/2011

Drug/Important Bio-Agent (IBA)

13Biomarkers (Surrogate Marker)IBA
10/2020 - 07/2014
8Amyloid (Amyloid Fibrils)IBA
01/2019 - 01/2015
5Proteins (Proteins, Gene)FDA Link
01/2021 - 03/2017
5Caspase 3 (Caspase-3)IBA
01/2019 - 06/2012
42- (6- chloro- 2- (4- (3- fluoropropoxy)phenyl)imidazo(1,2- a)pyridin- 3- yl)- N,N- diethylacetamideIBA
01/2021 - 03/2017
4Fluorodeoxyglucose F18 (Fludeoxyglucose F 18)FDA Link
01/2019 - 04/2017
4duramycinIBA
01/2018 - 12/2015
3Metabotropic Glutamate 5 ReceptorIBA
10/2020 - 01/2018
3Glutamic Acid (Glutamate)FDA Link
04/2020 - 11/2013
3micaIBA
03/2020 - 01/2019
3technetium 99m HYNIC-duramycinIBA
01/2018 - 01/2016
3Irinotecan (Camptosar)FDA LinkGeneric
01/2017 - 12/2015
2Glycoproteins (Glycoprotein)IBA
01/2022 - 01/2020
2EnzymesIBA
05/2020 - 05/2010
2Monoclonal AntibodiesIBA
03/2020 - 09/2019
2Metformin (Glucophage)FDA LinkGeneric
08/2019 - 01/2019
2Pharmaceutical PreparationsIBA
01/2019 - 01/2017
2LigandsIBA
01/2018 - 10/2012
2conatumumabIBA
01/2018 - 04/2017
2Fluorouracil (Carac)FDA LinkGeneric
01/2017 - 01/2016
2Urokinase-Type Plasminogen Activator (Urokinase)FDA Link
11/2016 - 07/2014
2Plasminogen Activator Inhibitor 1IBA
11/2016 - 07/2014
11- ((3- (methylpyridin- 4- yl)methyl)- 4- (3,4,5- trifluorophenyl)pyrrolidin- 2- oneIBA
01/2022
1Dopamine (Intropin)FDA LinkGeneric
01/2021
1PK 11195 (PK11195)IBA
01/2021
1SCH 23390IBA
01/2021
1Kainic Acid (Kainate)IBA
01/2021
13- (6- methylpyridin- 2- ylethynyl)cyclohex- 2- enone- O- methyloximeIBA
10/2020
1Apolipoproteins E (ApoE)IBA
05/2020
1Metabotropic Glutamate Receptors (Metabotropic Glutamate Receptor)IBA
04/2020
1Radioisotopes (Radionuclides)IBA
03/2020
1CyclooctanesIBA
03/2020
1Therapeutic UsesIBA
08/2019
13- fluoro- 2- (4- ((2- nitro- 1H- imidazol- 1- yl)methyl)- 1H- 1,2,3- triazol- 1- yl)propan- 1- olIBA
08/2019
1salicylhydroxamic acid (SHAM)IBA
01/2019
1GABA-A Receptors (GABA(A) Receptor)IBA
12/2017
1Immunoglobulin G (IgG)IBA
04/2017
1Staphylococcal Protein A (Protein A)IBA
03/2017
1ZincIBA
01/2017
1EndopeptidasesIBA
01/2017
1florbetapirIBA
01/2017
1Matrix Metalloproteinases (MMPs)IBA
01/2017
1QuinpiroleIBA
11/2016
1N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA
02/2016
1KynurenineIBA
02/2016
1Tryptophan (L-Tryptophan)FDA Link
02/2016
1N-Methylaspartate (NMDA)IBA
02/2016
1deoxyuridine triphosphateIBA
01/2016
1DNA Nucleotidylexotransferase (Terminal Deoxynucleotidyl Transferase)IBA
01/2016
1fluoromisonidazoleIBA
01/2016
12- (4'- (methylamino)phenyl)- 6- hydroxybenzothiazole (Pittsburgh compound B)IBA
12/2015
14- (N- methylamino)- 4'- (2- (2- (2- fluoroethoxy)ethoxy)ethoxy)stilbeneIBA
12/2015
1Glucose (Dextrose)FDA LinkGeneric
01/2015
1Plasminogen Activators (Plasminogen Activator)IBA
07/2014
1CytokinesIBA
10/2012
1Interleukin-1 (Interleukin 1)IBA
10/2012
1Eosine Yellowish-(YS) (Eosin)IBA
06/2012
1technetium Tc 99m glucarateIBA
06/2012
1Coloring Agents (Dyes)IBA
06/2012
1Hematoxylin (Haematoxylon)IBA
06/2012
1zinc(II) dipicolylamineIBA
06/2012
1Coordination ComplexesIBA
06/2011

Therapy/Procedure

8Therapeutics
01/2022 - 12/2015
3Radiotherapy
08/2019 - 01/2016
3Drug Therapy (Chemotherapy)
01/2018 - 12/2015
2Secondary Prevention
04/2017 - 01/2017
1Aftercare (After-Treatment)
04/2017